1950–1975: Progress Continues

The end of HIV: Still a very long way to go, but progress continues

In an Editorial accompanying PLOS Medicine's Special Issue on Advances in Prevention, Treatment and Cure of HIV/AIDS, Guest Editors Steven Deeks, Sharon Lewin, and Linda-Gail Bekker discuss priorities in the field and the content of the issue.

Progress continues in the quest to cure atrial fibrillation with catheter ablation techniques.

Over the past 5 years, the electrophysiology community has been focused on the development of catheter ablation techniques and ablation systems to cure atrial fibrillation. This endeavour has been fuelled by a number of factors including: (1) the clinical importance of atrial fibrillation because of its high prevalence in the general population, associated symptoms, stroke risk, and increased m...

Blunting sharps injuries in the OR continues to be a work in progress.

IPEJ: The journey continues.

Arise, awake, and stop not till the goal is reached e Katha Upanishad, chapter 1.3.14 Every journey starts with a small step forward, and every step in it carries a dream along. The initial steps in this journal's odyssey were by the founder editor, Prof: Johnson Francis, and he carried it as a dream formany years of this journey. Many joined him, nurtured the journal well and helped it grow up...

p53 continues to surprise

As one of the most intensively studied transcription factors, it is unsurprising that p53 is involved in many biological processes, including cell cycle arrest, DNA repair, senescence and apoptosis.1 its activities are mainly regulated by posttranslational modifications and interactions with other cellular components. Over the past few years, p53 has also been linked to redox homeostasis, the b...